It would be cool if one could safely adapt to modern life (lots of sitting, required focus over long sessions) without having to spend time exercising if they don't want to (to be clear, some people want to). Imagine if you could just take something to get all the benefits of exercise, without having to actually spend the time. That'd be pretty great for everyone if it truly was safe and without downsides (skeptical).
What if we could just lay in a pod 24/7 taking peptides and nutrient supplements while having an endless stream of instagram reals beamed in to our eyeballs on our Meta Raybans. That way we would never have to do pesky things like go outside or move.
On the other hand, a pill to replace all the un-fun activity needed to stay in shape while having a family and office job would let you enjoy fun activity a lot more, and want to do those things more often, since they’re all more-fun and safer if you’re already in shape.
They make stationary bikes that fit under a desk. I've never used or seen one, but they exist. I considered getting one during 2020, but they seemed impossible to source.
This study and most similar do not take into account bone density, this is a concern for women who have to actively build this up early in life to have a reserve (to account for the continual decline after about age 25 that is worse for women) to stave off osteoporosis - as well as continually work on maintenance after that with weight bearing/resistance exercise and diet. At least this is what I learned from my exercise and physiology textbook, the best antidote is building up of bone density in a woman's younger years and I doubt there's research into a substitute for that.
https://duckduckgo.com/?q=desk+stationary+bike
That's better than what i'm doing, hunched over my desk with the metabolic rate of a sleeping lemur, but...it's a slow stroll.