Most games use the sound support that comes with their game engine or choice of sound system, so I don't think the lack of an STB version is an issue. Performance is more of a problem. Audiokinetic, the makers of the popular Wwise audio system, estimate that Opus takes ~3-5x the CPU of Vorbis:
https://www.audiokinetic.com/en/community/blog/a-guide-for-c...